Sucrosomial Iron on Insomnia in Non-dialysis Chronic Kidney Disease Patients With Iron Deficiency Anemia

Inclusion Criteria: 1. Adults aged 20-80. 2. Chronic kidney disease (CKD) patients. 3. Iron deficiency anemia (male haemoglobin (Hb) ≤13 g/dL; female haemoglobin (Hb) ≤12 g/dL, ferritin ≤100 ng/mL, transferrin saturation ≤25%). 4. Patients diagnosed as chronic insomnia by doctors according to international classification of sleep disorders-third edition (ICSD-3). 5. Subjects who voluntarily participate in the trial plan and complete the consent form after explanation by doctors or project personnel. Exclusion Criteria: 1. Patients taking iron supplements. 2. Patients with non-chronic insomnia. 3. Patients with alcoholism within one year. 4. People with other serious diseases. 5. Pregnant women or women who are still breastfeeding. 6. Those who are unable to cooperate with the test progress. 7. Patients with autoimmune abnormalities (ex. inflammatory bowel disease). 8. People with non-iron deficiency anemia (ex. thalassemia). 9. Those who are taking sleeping pills or sedatives.