Vascular Affection in Behcet Disease

N/ANot Yet RecruitingNCT06280430

Assiut University90 enrolled

Overview

To measure the level of serum elafin in patients with behcet disease and to assess the correlation between serum elafin and vascular affection and their relation with disease activity

Behcet disease is a chronic multi systemic inflammatory disease characterized by recurrent oral and genital ulcers and multiple systemic affection . Elafin is a serine protease inhibitor produced mainly by epithelial cells . previous studies documented the role of serum elafin in pathogenesis of behcet disease.vascular complications may be one if the earliest manifestation leading to the diagnosis of behcet disease.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Behcet Disease and Vascular Involvement

Eligibility

Sex: ALLMin age: 20 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients diagnosed as behcet disease Age (20-45) Exclusion Criteria: * age \<20 and \>45 Other autoimmune diseases Risk factors (ischemic heart disease, diabetes) Chronic conditions (malignancy, chronic kidney disease)

Outcomes

Primary Outcomes

To measure the level of serum elafin in behcet patients and compare it with control group

Measure the level of serum elafin in behcet and its relation to disease activity and vascular involvement

Time frame: Within 1year

Data from ClinicalTrials.gov

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