Using national health insurance service database, current study aim to evaluate the risk and prognosis of acute myocardial infarction in cancer patients and to find the optimal treatment strategy for acute myocardial infarction that can improve long-term prognosis.
This study will be conducted using Korean National Health Insurance Service database. Patients who were diagnosed with cancer from 2002 to 2021 will be included in the study. Using the selected patients, current study will analyze the incidence and prognosis of acute myocardial infarction in cancer patients and the prognosis according to the treatment method for acute myocardial infarction will be compared. Primary outcome will be all-cause death. Secondary outcomes will be myocardial infarction, revascularization, hospitalization for heart failure, stroke, and clinically relevant bleeding.
Study Type
OBSERVATIONAL
Enrollment
4,500,000
Performing PCI or CABG
Chonnam National University Hospital, Chonnam National University Medical School
Gwangju, South Korea
All-cause death
All-cause death which was obtained from death certification collected by Statistics Korea at the Ministry of Strategy and Finance of South Korea
Time frame: 2-years after diagnosis of acute myocardial infarction
Myocardial infarction
Myocardial infarction is defined as presence of the diagnostic codes (ICD-10 I21, I22) in the primary position during hospitalization
Time frame: 2-years after diagnosis of acute myocardial infarction
Revascularization
Percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)
Time frame: 2-years after diagnosis of acute myocardial infarction
Hospitalization for heart failure
Heart failure events requiring hospitalization defined as presence of the diagnostic codes (I110, I130, I132, I255, I420, I425-I429, I43, I50, I971) in the primary position during hospitalization
Time frame: 2-years after diagnosis of acute myocardial infarction
Stroke
Stroke is defined as ischemic stroke (ICD-10 I63, I64) or intracranial hemorrhage (ICD-10 I60-62), combined with the codes of diagnostic brain imaging.
Time frame: 2-years after diagnosis of acute myocardial infarction
Clinically relevant bleeding
Bleeding requiring hospitalization or transfusion
Time frame: 2-years after diagnosis of acute myocardial infarction
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