A Study on the Relationship Between Gastric Xanthoma and Gastric Cancer and Precancerous Lesions

Xijing Hospital of Digestive Diseases1,260 enrolled

Overview

To explore the effects of gastric xanthoma on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.

This is a large-scale single center case-control study. Patients were consecutively enrolled and divided into gastric cancer group, gastric precancerous lesions group, and chronic gastritis group, according to histopathological results.Record the location and quantity of gastric xanthoma and situation of Helicobacter pylori infection in each patient.

Study Type

OBSERVATIONAL

Enrollment

1,260

Conditions

Gastric Xanthoma Helicobacter Pylori Infection Gastric Cancer Intestinal Metaplasia Precancerous Lesions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age range from 18 to 75 years old, regardless of gender; 2. Endoscopic/pathological diagnosis: chronic non atrophic gastritis/chronic atrophic gastritis/intestinal metaplasia/dysplasia Hyperplasia/gastric cancer 3. Voluntarily sign an informed consent form. Exclusion Criteria: 1. Previously underwent upper gastrointestinal surgery 2. Previous diagnosis of malignant tumors 3. Individuals who are unable to cooperate with the questionnaire survey due to mental disorders or other reasons 4. Those who cannot be observed by endoscopy due to acute upper gastrointestinal bleeding or other reasons

Locations (1)

Xijing Hosipital of Digestive Disease

Xi'an, Shaanxi, China

Outcomes

Primary Outcomes

corelation between the gastric xanthoma and gastric mucosa diseases

we evaluate the corelation between the gastric xanthoma and gastric mucosa diseases according to the histopathological results and the scales the patients finished

Time frame: up to 6 months

Data from ClinicalTrials.gov

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