Total hip arthroplasty is currently the most effective method for treating hip joint lesions and improving quality of life, but postoperative severe pain is not conducive to rapid recovery of patients. In recent years, the widespread application of ultrasound has achieved good clinical results in iliac fascia block for postoperative analgesia in THA. However, the use of high-dose local anesthetics can increase the risk of local anesthetic poisoning, and the single block analgesia time is generally less than 24 hours. Methylene blue, as a long-acting analgesic drug, can block the pain transmission of nerve fibers for a long time, achieving analgesic effects without damaging neurons. This study used ultrasound-guided ropivacaine combined with methylene blue to perform iliac fascia block on patients undergoing total hip replacement, with the aim of prolonging pain relief time, reducing complications, and promoting postoperative recovery on the basis of traditional methods.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
90
Ultrasound guided iliac fascia block, administered with 30ml of 0.25% ropivacaine+0.05% methylene blue
Jiangyan District Hospital of traditional Chinese medicine attached to the Nanjing University of Chinese Medicine
Taizhou, Jiangsu, China
Visual Analogue Scale（VAS）
Use a swimming ruler about 10 cm long, marked with 10 ticks on one side, and "0" and "10" at each end. A score of 0 indicates no pain, a score of 10 indicates the most severe pain that is unbearable, and the higher the score, the greater the degree of pain
Time frame: From enrollment to 48 hours after surgery， the VAS scores at both rest and with activity (passive straight leg raise at 45°) were recorded at the following time points: before block and at 2, 6, 12, 24, and 48 h postoperatively
Hypersensitive C-reactive Protein
Hypersensitive C-reactive protein, like procalcitonin, is an inflammatory marker. Both have the same meaning and are used to reflect the postoperative analgesic effect
Time frame: From enrollment to 48 hours after surgery
Procalcitonin
Procalcitonin is an inflammatory marker, which is associated with postoperative pain, the higher the degree of pain, the higher the procalcitonin value, the lower the pain level, and the lower the procalcitonin value, and the level of procalcitonin is used to reflect the postoperative analgesic effect
Time frame: From enrollment to 48 hours after surgery
Neutrophil Lymphocyte Ratio
Time frame: From enrollment to 48 hours after surgery
Mean Arterial Pressure
Time frame: From entering the operating room to leaving the resuscitation room
Heart Rate
Time frame: From entering the operating room to leaving the resuscitation room
Duration of Surgery
Time frame: Intraoperative
Number of Postoperative Salvage Analgesia
Time frame: From the end of surgery to 48 hours after surgery
Walking Distance for the First Time Getting Out of Bed
Time frame: From the end of surgery to 48 hours after surgery
The Number of Activities of Getting Out of Bed 48 Hours After Surgery
Time frame: From the end of surgery to 48 hours after surgery
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