The goal of this observational study is to evaluate the clinical efficacy of the transfusion of irradiated red blood cells, washed red blood cells, and leukocyte privative red blood cells, and to study the changes of inflammatory response before and after the transfusion of irradiated red blood cells, washed red blood cells, and leukocyte privative red blood cells in anemic neonates. The main questions it aims to answer are: * Objective evaluation of the advantages and disadvantages of transfusion of different blood products in the treatment of neonatal anemia from the clinical efficacy. * To provide objective basis for clinical rational use of blood in the selection of blood products. Participants will be transfused with fresh irradiated red blood cells, washed red blood cells, and leukocyte privative red blood cells respectively according to relevant clinical and laboratory indicators.
Study Type
OBSERVATIONAL
Enrollment
200
Transfusion of designated red blood cell products to anemic neonates.
Women's Hospital School of Medicine Zhejiang University
Hangzhou, Zhejiang, China
Clinical efficacy of different red blood cell products transfusion in anemic neonates
The changes of hemoglobin concentration, crSo2 and cFTOE before and after transfusion were detected to evaluate the effects of different red blood cell products on brain oxygenation capacity of anemic neonates.
Time frame: The test results of each subject before and 24 hours after blood transfusion were analyzed.
The changes of inflammatory response before and after transfusion in anemic neonates
IL-6, IL-10 and CRP levels were measured, and the effect of infusion of different red blood cell products on the potential inflammatory response of anemic neonates was evaluated.
Time frame: The test results of each subject before and 24 hours after blood transfusion were analyzed.
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