This study evaluates the efficacy and safety of adding the SGLT-2 inhibitor DA5221-T to the combination therapy of DA5221-B1 and the DPP-4 inhibitor DA5221-B2 in patients with type 2 diabetes who have inadequate blood glucose control. The study focuses on assessing the effectiveness and safety of the triple combination therapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
174
Severance Hospital, Yonsei University college of Medicine
Seoul, South Korea
Change from the baseline in HbA1c (%) after 24 weeks
Time frame: Baseline, 24 weeks
Change from the baseline in fasting plasma glucose(mg/dL) after 24 weeks
Time frame: Baseline, 24 weeks
Change from the baseline in HbA1c response rate(<7.0%, <6.5%) after 24 weeks
Time frame: Baseline, 24 weeks
Change from the baseline in weight after 24 weeks
Time frame: Baseline, 24 weeks
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DA5221-B1, orally, daily for background therapy
DA5221-B2, orally, daily for background therapy