Poor responders in in-vitro fertilization (IVF) cycles represent a major challenge for fertility specialists. Although poor responders tend to have sub-optimal fertility treatment outcomes, many of these patients wish to attempt at least one IVF cycle. Traditionally, IVF cycles producing less than 3 to 4 mature follicles (measuring at least 14 mm) have either been cancelled or converted to intra-uterine insemination (IUI) due to the low pregnancy rates associated with these cycles. The minimal number of follicles required to proceed with egg collection is based on clinical experience, having been determined by weighing the probability of implantation and pregnancy versus the risk of not obtaining quality oocytes or reaching embryo transfer when fewer mature follicles are present. This retrospective quality control study aims to compare pregnancy rates in IVF cycles producing 3 follicles measuring 14 mm and more on trigger day, versus 2 or fewer follicles.
Study Type
OBSERVATIONAL
Enrollment
405
Ovulation triggering when women only 2 dominant follicles as opposed to the clinic's standard of 3 follicles or more
Clinique Ovo
Montreal, Quebec, Canada
Clinical Pregnancy Rate
clinical pregnancy is the presence of fetal heartbeat at the viability ultrasound
Time frame: 6 to 8 weeks after Frozen Embryo Transfer
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