Autism spectrum disorders (ASDs) are characterized by core domains: persistent deficits in social communication and interaction; restricted, repetitive patterns of behavior, interests, or activities.
Autism spectrum disorders (ASDs) are characterized by core domains: persistent deficits in social communication and interaction; restricted, repetitive patterns of behavior, interests, or activities. ASDs comprise heterogeneous and complex neuro-developmental pathologies with well-defined inflammatory conditions and immune system dysfunction. Due to neurobiological changes underlying ASD development, cell-based therapies have been proposed and applied to ASDs. Indeed, stem cells show specific immunologic properties, which make them promising candidates for ASD treatment.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
14
\- Patients receive three intravenous doses of MSCs (1 million/kg) every two weeks as treatment.
Cell Therapy Center
Amman, Jordan
RECRUITINGsafety profile lab tests
-patients will be monitored for any possible adverse events resulting from the injection of MSCs.
Time frame: follow-up duration is 12 months
efficacy change in Adult ADHD Self-Report Scale (ASRS)
-The subjects will be monitored with ASRS at baseline, 3, 6, 9, and 12 months
Time frame: follow-up duration is 12 months
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