Environmental noise represents a health problem for at least one in five citizens of the European Union. Noise exposure leads to the development of arterial hypertension, myocardial infarction, stroke, and obesity. Given the limited information on noise exposure and noise effects on humans in the Republic of Serbia, the overall objective of NOXYCARD is to collect environmental noise levels data; to identify long-term and short-term noise effects on the cardiovascular system; and to evaluate the levels of blood stress hormones, oxidative stress, and inflammation in individuals with normal body weight and individuals with obesity.
Study Type
OBSERVATIONAL
Enrollment
150
Participants of both arms will be exposed to the same loud pre-recorded road traffic noise in a laboratory setting.
Faculty of Medicine, University of Belgrade
Belgrade, Beograd, Serbia
Systolic blood pressure
Systolic blood pressure in mmHg, higher values indicate high risk
Time frame: 10, 40, and 50 minutes
Concentration of stress hormone
Cortisol level in mcg/dL, higher values indicate high risk
Time frame: 10, 40, and 50 minutes
Diastolic blood pressure
Diastolic blood pressure in mmHg, higher values indicate high risk
Time frame: 10, 40, and 50 minutes
Concentration of inflammation parameters
Interleukin-1-Beta levels in pg/mL, higher values indicate high risk
Time frame: 10, 40, and 50 minutes
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