The primary objective of the study is to evaluate real-world effectiveness of treatment with Repatha® in combination with SOC, compared with SOC alone, on the risk for cardiovascular (CV) death, myocardial infarction (MI), stroke, hospitalization for unstable angina, or coronary revascularization, whichever occurs first, in participants with established atherosclerotic CV disease (ASCVD) treated with SOC, according to local clinical practice.
Study Type
OBSERVATIONAL
Enrollment
7,000
China Japan Friendship Hospital
Beijing, Beijing Municipality, China
RECRUITINGPeking University First Hospital
Beijing, Beijing Municipality, China
RECRUITINGFuwai Hospital Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China
RECRUITINGBeijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Time to CV Death, MI, Hospitalization for Unstable Angina, Stroke, or Coronary Revascularization, Whichever Occurs First
Time frame: Up to 72 months
Time to CV Death, MI, or Stroke, Whichever Occurs First
Time frame: Up to 72 months
Change in Low-density Lipoprotein Cholesterol (LDL-C) From Baseline
Time frame: Baseline and end of follow-up (up to 72 months)
Percent Change in LDL-C From Baseline
Time frame: Baseline and end of follow-up (up to 72 months)
Number of Participants Who Experienced Adverse Events
Time frame: Up to 72 months
Number of Participants Who Experienced Adverse Drug Reactions
Time frame: Up to 72 months
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Beijing Haidian Hospital
Beijing, Beijing Municipality, China
RECRUITINGPeking University Third Hospital
Beijing, Beijing Municipality, China
RECRUITINGBeijing Hospital
Beijing, Beijing Municipality, China
RECRUITINGChongqing Emergency Medical Center
Chongqing, Chongqing Municipality, China
RECRUITINGChongqing General Hospital
Chongqing, Chongqing Municipality, China
RECRUITINGDongguan Songshan Lake Central Hospital
Dongguan, Guangdong, China
RECRUITING...and 80 more locations