Acute obstructive pyelonephritis is a condition with a high risk of complications and may require admission to the intensive care unit. Most of the available data on this condition comes from small, retrospective, single-centre series. To date, no large-scale study has examined the factors associated with the prognosis of patients admitted to intensive care for acute obstructive pyelonephritis. The aim of this study is to describe the population and prognosis of patients admitted to the intensive care unit for the management of acute obstructive pyelonephritis, and to identify factors associated with a poor prognosis in these patients.
The retrospective and multicenter study consists of a retrospective and pseudonymous collection of data from medical reports of patients treated, over the period 2015-2022, in each intensive care unit agreeing to participate, . Investigators from each participating center will be responsible for screening on all hospitalized patients over the period 2015-2022. Patients who have been hospitalized for the management of acute obstructive pyelonephritis will be included, in the absence of non-inclusion criteria.
Study Type
OBSERVATIONAL
Enrollment
1,000
Hospital Saint Louis
Paris, France
RECRUITINGThe primary endpoint will be a combined endpoint of death, and/or stage 3 AKI ( KDIGO classification), and/or non-recovery of renal function.
Time frame: up to 30 days after admission to intensive care
Death
Time frame: up to 30 days after admission to intensive care
Stage 3 Acute kidney injury (KDIGO classification)
Time frame: up to 30 days after admission to intensive care
failure to recover renal function
defined as creatinine levels greater than 150% of baseline value
Time frame: up to 30 days after admission to intensive care .
the incidence of acute renal failure defined by KDIGO 1
Time frame: up to 30 days after admission to intensive care
the incidence of acute renal failure defined by KDIGO 2 and 3
Time frame: up to 30 days after admission to intensive care
the incidence of Renal replacement therapy
Time frame: up to 30 days after admission to intensive care
the incidence of non-recovery of renal fuction
Time frame: up to 30 days after admission to intensive care
The number of days alive without Renal replacement therapy
Time frame: up to 30 days after admission to intensive care
The number of days alive without catecholamines
Time frame: up to 30 days after admission to intensive care
The number of days alive without antibiotics
Time frame: up to 30 days after admission to intensive care
The number of days alive without
Time frame: up to 30 days after admission to intensive care
Death rate
Time frame: up to 30 days after admission to intensive care
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