To compare the incidence of the composite endpoints of non-fatal ischaemic stroke, transient ischaemia (TIA) and all-cause mortality at 12-month follow-up after implantation of Bridge for the treatment of symptomatic vertebral artery stenosis in subjects who had been taking different durations of dual-antiplatelet therapy (3 vs 6 months) and ticagrelor monotherapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
560
To compare the safety and efficacy of different DAPT duration combined with ticagrelor monotherapy.
the Fourth Affiliated Hospital of China Medical University
Shenyang, Liaoning, China
RECRUITINGIncidence of the composite endpoint of non-fatal ischaemic Stroke, TIA, and all-cause mortality at 12-months.
Time frame: 365±60 days
Incidence of the composite endpoint of major bleeding and hemorrhagic stroke at 12-months.
Time frame: 365±60 Days
Incidence of target vessel-related stroke and neurological death at 1month
Time frame: 30±7 Days
Incidence of stroke and neurological death at 12 month.
Time frame: 365±60 Days
Incidence of all-cause mortality at 12 month.
Time frame: 365±60 days
Incidence of in-stent-stenosis at 12 month (subgroup of imaging follow-up).
Time frame: 365±60 days
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