Effect of Intravenous Dexmedetomidine Versus Dexamethasone for Management of Repound Pain After Supraclavicular Brachial Plexus Block

Assiut University111 enrolled

Overview

Effect of intravenous dexmedetomidine versus dexamethasone for management of repound pain after supraclavicular brachial plexus block.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

111

Conditions

Trauma Injury

Interventions

Dexmedetomidine injectionDRUG

Dexmedetomidine group will receive 0.5 mcg/kg

DexamethasoneDRUG

Dexamethasone group will receive 8mg/kg

SalineDRUG

receive equivalent volume of saline 0.9%.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients between 20\_60 years old * Patients with ASA clinical status I/II * Patients scheduled for peripheral nerve block for upper extremity surgery Exclusion Criteria: * 1\) they refused to participate 2) had preexisting neuropathy of the surgical limb 3) hypersensitivity to amide anesthetic 4) significant pulmonary disease 5) coagulopathy 6) sepsis 7) infection at the block site 8) hypersensitivity to dexmedetomidine \& dexamethasone

Locations (1)

Marwa Mahmoud Rady

Asyut, Assiut Governorate, Egypt

Outcomes

Primary Outcomes

The incidence of rebound pain.

Rebound pain is defined as an increase from well-controlled to severe pain typically within 12\_24 h of resolution of the nerve block.

Time frame: 1year

Data from ClinicalTrials.gov

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