To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
60
consume 1 bottle per day
consume 1 bottle per day
Chia Nan University of Pharmacy & Science
Pingtung City, Taiwan
The change of skin hydation
Corneometer® CM825 (CK, Germany) was utilized to measure skin surface hydation. Units: arbitrary Corneometer® units 0-120.
Time frame: Change from Baseline skin skin hydation at 12 weeks
The change of skin wrinkles
VISIA Complexion Analysis was utilized to measure skin wrinkles. Units: the amount of detectable wrinkles
Time frame: Change from Baseline skin wrinkles at 12 weeks
The change of skin elasticity
Cutometer® MPA580 was utilized to measure skin elasticity. Units: visco-elasticity in %.
Time frame: Change from Baseline skin elasticity at 12 weeks
The change of skin collagen density
DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units
Time frame: Change from Baseline skin collagen density at 12 weeks
The change of hair diameters
Mitutoyo C/N293-100 was utilized to measure hair diameters. Units: millimeter
Time frame: Change from Baseline hair diameters at 12 weeks
The change of hair loss amount
Collect and measure the weight of loss hair. Units: gram
Time frame: Change from Baseline hair loss amount at 12 weeks
The change of hair roots diameters
Mitutoyo C/N293-100 was utilized to measure hair roots diameters. Units: millimeter
Time frame: Change from Baseline hair roots diameters at 12 weeks
The change of hair density
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Soft Plus was utilized to picture and observe hair density.
Time frame: Change from Baseline hair density at 12 weeks
The change of hair follicle strength
Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area. Units: the number of loss hair
Time frame: Change from Baseline hair follicle strength at 12 weeks
The change of thumbs nail color
Chroma Meter MM500 was utilized to measure thumbs nail color. Units: L\* index
Time frame: Change from Baseline thumbs nail color at 12 weeks
The change of nails appearence
Picture taken was utilized to record and observe nails appearence.
Time frame: Change from Baseline nails appearence at 12 weeks
The change of nails growth
Marking the position of middle fingers lunula was utilized to record and observe nails growth. Units: milimeter
Time frame: Change from Baseline marking position at 12 weeks
The degree of nails fragility
Iron ruler was utilized to evaluate nails fragility. Picture taken was utilized to record and observe the change of nails fragility.
Time frame: Change from Baseline nails fragility at 12 weeks
The change of self-assessment skin, hair, and nails condition
A self-assessment questionnaire was collected and evaluate skin, hair, and nails condition
Time frame: Change from Baseline skin, hair, and nails condition at 12 weeks