The main objective of this study is to study the bioavailability and kinetics of acute Aronia Melanocarpa supplementation in healthy young (18-35 years) and older adults (55-75 years) adults. During the test day, participants will ingest a drink consisting of Aronia Melanocarpa extract (AME). The bioavailability and kinetics of AME will be assessed via frequent blood sampling, urine collection, and faecal sampling, in which AME and metabolite profiles will be quantified.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
16
Aronia Melanocarpa extract (AME) consisting of a mixture of anthocyanins and other polyphenols
Maastricht University
Maastricht, Netherlands
RECRUITINGAronia metabolites in blood
Concentrations and quality of Aronia metabolites in blood analysed with LC-MS
Time frame: time = 0 hours until t = 48 hours
Aronia metabolites in urine
Concentrations and quality of Aronia metabolites in urine analysed with LC-MS
Time frame: time = 0 hours until t = 48 hours
Aronia metabolites in feces
Concentrations and quality of Aronia metabolites in feces analysed with LC-MS
Time frame: time = 0 hours
length - baseline characteristics
length
Time frame: time = 0 hours
weight - baseline characteristics
weight
Time frame: time = 0 hours
blood pressure (systolic and diastolic) - baseline characteristics
blood pressure
Time frame: time = 0 hours
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