Calcified Cerebral Embolism: a Descriptive Study in a Large Single Center Cohort

Centre Hospitalier Universitaire de Nīmes79 enrolled

Overview

Calcified cerebral embolism (CCE) is a relatively rare but underdiagnosed cause of infarction. CCE diagnosis is made by CT. Radiological characteristics of CCE have been reported in small case series. The aim of this study was to describe clinical and radiological characteristics of CCE in a large number of patients, and to compare patients with different radiological CCE characteristics.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Calcified Cerebral Embolism

Interventions

None, purely observational studyOTHER

None, purely observational study

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with CEE treated with intravenous thrombolysis (IVT) between 2015 and 2020 managed at the CHU de Nîmes or Patients with TIA/stroke with ECC identified on CT between 12/2019 and 04/2023 managed at CHU de Nîmes Exclusion Criteria: * Patient's refusal to use his/her data

Locations (1)

CHU de Nîmes

Nîmes, France

Outcomes

Primary Outcomes

Calcified aortic brachiocephalic

looking for calcified aortic brachiocephalic (presence or absence)

Time frame: baseline

cardiovascular risk

Study of cardiovascular risk factors (presence or absence)

Time frame: baseline

history of stroke

Presence of a history of stroke (y/n)

Time frame: baseline

Population

demographic characteristics age (years)

Time frame: baseline

Population

demographic characteristics sexe (M/F)

Time frame: baseline

history of surgical/endovascular cardiovascular intervention

surgical/endovascular cardiovascular intervention (y/n)

Time frame: baseline

NIHSS

NIHSS score (Score between 1 and 4: minor stroke, Score between 5 and 15: moderate, stroke, Score between 15 and 20: severe stroke) Score \> 20: severe stroke

Time frame: baseline

calcified aortic arch

looking for calcified aortic arch (presence/absence)

Time frame: baseline

calcified carotid

looking for calcified carotid (presence/absence)

Time frame: baseline

Data from ClinicalTrials.gov

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