This retrospective monocentric comparative study aims to assess the efficacy of preoperative ischemic conditioning, in preventing anastomotic leakage in esophageal cancer surgery. Two groups were included : a surgery-alone group (control group) and a PreopAE group (study group) treated with an embolization procedure before esophagectomy. Collected data included patient characteristics, embolization procedure details, surgical outcomes, and postoperative complications. The primary outcome was the efficacy of preoperative ischemic conditioning in preventing anastomotic leakage, assessed through CT scans. Secondary outcomes included analyzing safety of ischemic gastric conditioning, hypertrophy of the gastroepiploic artery in embolized patients and comparing hospital stay length and postoperative mortality.
Study Type
OBSERVATIONAL
Enrollment
50
Collecting data from the medical record: * Gastroepiploic artery diameter before and after ischaemic preconditioning * Postoperative mortality * Complications related to embolisation and surgery * Length of stay in intensive care unit and total length of hospital stay
CHU de Saint-Etienne
Saint-Priest-en-Jarez, France
Measurement of the effectiveness of preoperative ischaemic conditioning in reducing anastomotic leakage in patients undergoing oesophagectomy.
Radiological confirmation by thoracoabdominal CT scan with oral contrast showing dehiscence of the oesophagastric anastomosis will be sought.
Time frame: Day : 90
Measurement of the effectiveness of preoperative ischaemic conditioning in reducing anastomotic leakage in patients undergoing oesophagectomy.
Dehiscence confirmed by the surgeon during a repeat operation will be sought.
Time frame: Day : 90
Measurement of the effectiveness of preoperative ischaemic conditioning in reducing anastomotic leakage in patients undergoing oesophagectomy.
Endoscopic confirmation of an anastomotic leak will be sought.
Time frame: Day : 90
Safety of ischemic gastric conditioning
Safety of ischaemic gastric filling will be analysed on the basis of imaging and data recordings.
Time frame: Day : 90
Hypertrophy of the gastroepiploic artery
Hypertrophy of the gastroepiploic artery in embolized patients will be analysed on the basis of imaging and data recordings.
Time frame: Day : 90
Comparing hospital stay length
Hospital stay length will be analysed on the basis of data recordings.
Time frame: Day : 90
Comparing postoperative mortality
Postoperative mortality will be analysed on the basis of data recordings.
Time frame: Day : 90
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