The goal of this retrospective observational study is to find out the effects of probiotics on HBV clearance. The main question it aims to answer is: Are the probiotics have an effect in promoting HBV clearance? The participants will observe the HBV clearance rate in chronic hepatitis B patients receive probiotics in addition to the routine antiviral therapy. Researchers will compare the HBV clearance rate in chronic hepatitis B patients receive probiotics and antiviral therapy with those receiving solely antiviral therapy.
Study Type
OBSERVATIONAL
Enrollment
40
The patients receive PegIFNα2b therapy
The patients receive both PegIFNα2b and probiotics therapy
The patients receive nucleoside analog therapy
Qilu Hospital of Shandong University
Jinan, Shandong, China
RECRUITINGHBsAg clearance
Time frame: 48 months
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The patients receive both nucleoside analog and probiotics therapy