The Use of Drospirenone/Estetrol in Random Start Rapid Endometrial Preparation

University of Palermo80 enrolled

Overview

The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety of drugs. We explored the efficacy of random started 14-day administration of drospirenone/estetrol, in rapid preparation of endometrium for hysteroscopic polypectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Endometrial Polyp Endometrial Diseases

Interventions

drospirenone/estetrol 3mg/14.2mgDRUG

Hysteroscopic polipectomy after starting 14-day treatment with oral drospirenone/estetrol 3mg/14.2mg at any time of the menstrual cycle.

Eligibility

Sex: FEMALEHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with endometrial polyps. Exclusion Criteria: * Patients with other endometrial pathologies.

Locations (2)

Andrea Etrusco

Palermo, Italy

Marco Monti

Rome, Italy

Outcomes

Primary Outcomes

Quality of endometrial preparation

Quality of endometrial preparation assessed visually intraoperatively by the surgeon using a visual analog scale from 0 to 5.

Time frame: Intraoperatively

Data from ClinicalTrials.gov

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