The Use of Nomegestrol Acetate/Estradiol in Random Start Rapid Endometrial Preparation

University of Palermo80 enrolled

Overview

The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety of drugs. We explored the efficacy of random started 14-day administration of Nomegestrol Acetate/Estradiol, in rapid preparation of endometrium for hysteroscopic polypectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Endometrial Polyp Endometrial Diseases

Interventions

Nomegestrol Acetate/Estradiol 2.5mg/1.5mgDRUG

hysteroscopic polipectomy after starting 14-day treatment with oral Nomegestrol Acetate/Estradiol 2.5mg/1.5mg at any time of the menstrual cycle

Eligibility

Sex: FEMALEHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with endometrial polyps. Exclusion Criteria: * Patients with other endometrial pathologies.

Locations (2)

Andrea Etrusco

Palermo, Italy

Marco Monti

Rome, Italy

Outcomes

Primary Outcomes

Quality of endometrial preparation

Quality of endometrial preparation assessed visually intraoperatively by the surgeon using a visual analog scale from 0 to 5.

Time frame: 14th day of treatment

Data from ClinicalTrials.gov

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