The objective of this clinical trial is to investigate the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) in the cerebellum for individuals with post-stroke cognitive impairment. Participants will undergo rTMS in the cerebellar hemisphere opposite the lesion site, once daily for a total of five days.
The primary objective of this clinical trial is to investigate the effectiveness and safety of intermittent theta burst stimulation ( iTBS) in the cerebellum for individuals with post-stroke cognitive impairment. The trial aims to answer two main questions: (1) What is the effectiveness of iTBS in improving post-stroke cognitive impairment? (2) Is iTBS in the cerebellum safe for individuals with post-stroke cognitive impairment? Participants will undergo iTBS in the cerebellar opposite the lesion site, twice daily for five days. The control group will receive sham rTMS with the same parameters and positions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
70
iTBS on the contralesional cerebellum, twice a day for seven days
shame stimulation on the contralesional cerebellum, twice a day for seven days
Beijing Tiantan hospital
Beijing, China
RECRUITINGThe efficacy of improving cognitive function of post-stroke cognitive impairment
The change of MoCA between baseline and 3 months follow-up
Time frame: 3 months follow-up after treatment
The safety of improving cognitive function of post-stroke cognitive impairment
Incidence of epilepsy during treatment
Time frame: day1-day7
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