BReath Hold TecHniquEs for Radiotherapy of Esophageal Carcinoma

University Medical Center Groningen1 enrolled

Overview

The main objective of the first part of the study is to determine the most optimal method for DIBH (active breathing control vs voluntary coached) and its reproducibility. Based on these findings, one of these methods will be selected for part 2 of this study.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Esophageal Cancer

Interventions

DIBH using ABC techniqueOTHER

Deep breath inspiration hold (DIBH) using Active Breathing Control (ABC) technique

DIBH using VC techniqueOTHER

Deep breath inspiration hold (DIBH) using Voluntary Coaching (VC) technique

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Histologically proven esophageal cancer of the mid or distal esophagus * Scheduled for external-beam photon radiotherapy with curative intention. * WHO 0-2. * Age \>= 18 years * Written informed consent. Exclusion Criteria: * Serious respiratory distress * Contra-indication for fiducial marker placement * Noncompliance with any of the inclusion criteria

Locations (1)

UMC Groningen

Groningen, Netherlands

Outcomes

Primary Outcomes

Feasibility DIBH

Breath hold maintained for \>20 seconds

Time frame: Week 1, 2, 3, 4, 5 during radiotherapy

Reproducibility DIBH

Diaphragm dome position within 1cm of the baseline CT Target coverage \>94% of the prescribed dose (at 98% of the ITV)

Time frame: Week 1, 2, 3, 4, 5 during radiotherapy

Data from ClinicalTrials.gov

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