The study investigates whether patients with mild SARS-CoV-2 infection, who stayed at home during their infection and weren't hospitalized, have any persisting sequelae in pulmonary function. Therefore, 110 patients, aged 6-60 years, were recruited by telephone 4-12 weeks after laboratory-confirmed positive PCR and invited for a lung function testing. Every patient with abnormalities in pulmonary function was invited to a follow-up 3 months after the first appointment to assess changes in lung function values. Patients with a pre-existing lung disease and smokers within the last five years were excluded beforehand. Additionally to lung function testing we did a throat swab at each appointment to analyse via Multiplex PCR whether the patients had any other respiratory infection at the time of the pulmonary function testing.
110 patients, 90 adults and 20 children, were recruited. The lung function included LCI, FEV1, FVC and DLCO (Hb corrected). Additionally we did a throat swab at each appointment to analyse via Multiplex PCR whether the patients had any other respiratory infection at the time of the test.
Study Type
OBSERVATIONAL
Enrollment
110
lung function testing including LCI, FEV1, FVC, DLCO
Kinder- und Jugendklinik Universitätsmedizin Rostock
Rostock, Germany
Pulmonary function
Pulmonary function after SARS-CoV-2 Infection
Time frame: 4.3 - 11.3 weeks after positive PCR for SARS-CoV-2
Changes in pulmonary function
Changes in pulmonary function towards the follow-up
Time frame: 11.0 - 16.7 weeks after the first lung function testing
Sociodemographic factors
Relation of pulmonary function to sociodemographic factors
Time frame: 9 months
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