The purpose of this study is to evaluate the drug levels of mezigdomide in participants with renal impairment.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
26
Specified dose on specified days
PANAX
Miami Lakes, Florida, United States
Omega Research Group - Orlando
Orlando, Florida, United States
Orlando Clinical Research Center OCRC
Orlando, Florida, United States
Maximum observed concentration (Cmax)
Time frame: Up to 24 days
Area under the plasma concentration-time curve (AUC)
Time frame: Up to 24 days
Area under the plasma concentration-time curve from time 0 to time of last quantifiable concentration (AUC(0-T))
Time frame: Up to 24 days
Number of participants with adverse events (AEs)
Time frame: Up to 54 days
Number of participants with serious adverse events (SAEs)
Time frame: Up to 54 days
Number of participants with physical examination findings
Time frame: Up to 24 days
Number of participants with vital sign abnormalities
Time frame: Up to 24 days
Number of participants with 12-lead electrocardiogram (ECG) findings
Time frame: Up to 24 days
Maximum observed concentration (Cmax)
Time frame: Up to 24 days
Time of maximum observed concentration (Tmax)
Time frame: Up to 24 days
Area under the plasma concentration-time curve (AUC)
Time frame: Up to 24 days
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