Effect of Intravenous 5% Dextrose Infusion During Recovery from Anesthesia on the Quality of Early Postoperative Recovery in Patients Undergoing Painless Gastrointestinal Endoscopy

N/ACompletedNCT06319144

Weifang Medical University102 enrolled

Overview

The aim of this study was to determine the effect of intravenous infusion of 5% dextrose injection during the recovery period of anesthesia for painless gastroenteroscopy on the patient's blood glucose level, incidence of hypoglycemia and time of awakening from anesthesia, postoperative vertigo, postoperative nausea and vomiting, and quality of recovery in the early postoperative period.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

102

Conditions

Insulin Resistance Postoperative Nausea and Vomiting Quality of Recovery Dizzyness

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 79 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. patients who meet the indications for painless gastrointestinal endoscopy and are aged 18 to 79 years. 2. The patient or his/her guardian or immediate family members gave informed consent; 3. American Society of Anesthesiology (ASA) anesthesia risk classification ≤ grade III. Exclusion Criteria: 1. Patients with contraindications to sedation/anesthesia for gastrointestinal endoscopy: e.g., severe hepatic and renal dysfunction, cardiac insufficiency; 2. Patients receiving chemotherapy and opioid treatment; patients with a history of sleep apnea hypoventilation syndrome; 3. Intravenous nutritional support within 8 hours prior to the examination; 4. Patients diagnosed with type I or type II diabetes.

Outcomes

Primary Outcomes

Preoperative blood glucose 30min

A fingertip blood glucose concentration of \<3.9 mmol/L was used as a diagnostic criterion for hypoglycemia. Severity and incidence of hypoglycemia at 0.5 hours Preoperative.

Time frame: Measurements taken 0.5 hours Preoperative.

Postoperative blood glucose 2h

A fingertip blood glucose concentration of \<3.9 mmol/L was used as a diagnostic criterion for hypoglycemia. Severity and incidence of hypoglycemia at 2 hours postoperatively.

Time frame: Measured at 2 hours postoperatively.

Dizziness level

The Visual Analogue Scale(VAS) was used to assess the degree of postoperative dizziness in patients undergoing painless gastroenteroscopy.

Time frame: Approximately 15min after surgery

Dizziness level

The visual analogue scale (VAS) was used to assess the degree of postoperative dizziness in patients undergoing painless gastroenteroscopy.

Time frame: Measured at 0.5 hours postoperatively.

Postoperative nausea and vomiting

The Index of Nausea and Vomiting and Retching (INVR) was used in this study. The scale consists of 8 items with 3 dimensions, which can quantify the number of occurrences, duration and severity of symptoms. The scale is scored using the Likert method, with a total of 32 points on a 5-point scale ranging from 0 to 4. The higher the score, the more severe the symptoms of nausea, vomiting, and dry heaving (entries 1, 6, and 7 are reverse scored). According to the score, nausea, vomiting and dry heaving symptoms can be categorized into five grades: 0, I, II, III and IV, and grade ≥I means that the symptom occurs. The severity and incidence of PONV at 0.5 hours postoperatively.

Time frame: Measured at 0.5 hours postoperatively.

Postoperative nausea and vomiting

Time frame: Measured at 2 hours postoperatively.

Secondary Outcomes

Anesthesia awakening time

The clinical routine defines the time of awakening from anesthesia as the time between the cessation of anesthesia administration and the opening of the patient's eyes on call.

Time frame: Approximately 30min after surgery

Quality of postoperative recovery (QoR40)

The QoR-40 scale provides a true and valid reflection of the impact of various factors on the quality of postoperative recovery.

Time frame: Approximately 24hours after surgery