Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU

Hospital Clinico Universitario de Santiago1,036 enrolled

Overview

Tracheal intubation in the intensive care unit (ICU) is associated with high incidence of difficult intubation and complications. Videolaryngoscopes (VLs) devices have been proposed to improve airway management, and the use of VLs are recommended as first-line or after a first-attempt failure using direct laryngoscopy in ICU airway management algorithms. Although until relatively few years ago there were doubts about whether videolaryngoscopes had advantages over direct laryngoscopy for endotracheal intubation (ETI) in critically ill patients, two recent studies (DEVICE (1), INTUBATE (2)), and a Cochrane review (3) have confirmed that videolaryn should be used?, and what is the best blade? . There are two types of blades commonly used with videolaryngoscopes: the "Macintosh" blade with a slight curvature, and hyperangulated blades. The "Macintosh" blades have a lower angle of vision, but they have the advantage of being similar to the blades commonly used in direct laryngoscopy, making them easy to use for the person performing the ETI. Hyperangulated blades have a greater angle of vision, improving glottic visualization, especially in patients with an anterior glottis. However, the need to overcome this angulation could potentially hinder the passage of the endotracheal tube to the vocal cords. It is unknown if either blade has any advantage for intubating critically ill patients.

The purpose of this prospective multicenter randomized study is to compare successful intubation on the first attempt with the Macintosh videolaryngoscope vs the hyperangulated videolaryngoscope during tracheal intubation in ICU patients.The hypothesis of the study is that tracheal intubation using the hyperangulated videolaryngoscope will improve the frequency of successful intubation on the first attempt in ICU patients requiring intubation in the intensive care unit.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 years or older. * Admitted to an Intensive Care Unit. * Need for tracheal intubation during the stay in the ICU. * The device to be used for intubation is a videolaryngoscope Exclusion Criteria: * Pregnancy or lactation. * Emergent tracheal intubation that does not allow for the randomization of the procedure. * Need for tracheal intubation with a device other than the videolaryngoscope (fiberoptic bronchoscope, direct laryngoscopy, tracheostomy, etc.). * Tracheal intubation performed outside the ICU (Emergency Department, Hospital ward, etc.).

Locations (29)

University Clinical Hospital of Santiago de Compostela

Santiago de Compostela, A Coruña, Spain

RECRUITING

Complexo Hospitalario Universitario de A Coruña

A Coruña, Spain

RECRUITING

Hospital General de Albacete

Albacete, Spain

NOT_YET_RECRUITING

Hospital de la Santa Creu i Sant Pau, Barcelona

Barcelona, Spain

Outcomes

Primary Outcomes

Difference in the first attempt intubation success rate (percentage)

The primary outcome is defined as placement of an endotracheal tube in the trachea with a single insertion of a videolaryngoscope blade into the mouth and either a single insertion of an endotracheal tube into the mouth or a single insertion of a bougie into the mouth followed by a single insertion of an endotracheal tube over the bougie into the mouth.

Time frame: During intubation (minutes)

Secondary Outcomes

Difference in the overall success rate

To compare the difference overall success rate (percentage) with the two (hyperangulated vs Macintosh blades) videolaryngoscopes

Time frame: During intubation (minutes)

Number of intubation attempts

To compare number of intubations attempts with the two (hyperangulated vs Macintosh blades) videolaryngoscopes

Time frame: During intubation (minutes)

Modified Cormack-Lehane grade of glottic view

To compare Cormack-Lehane grade of glottic view with the two (hyperangulated vs Macintosh blades) videolaryngoscopes. Modified Cormack-Lehane grade of glottic view is defined as: Grade I: full view of the glottis Grade IIa: partial view of the glottis Grade IIb: arytenoid or posterior part of the vocal cords just visible Grade III: only epiglottis visible Grade IV: neither glottis nor epiglottis visible Cormack-Lehane grade of glottic view

Time frame: During intubation (minutes)

Diference in the incidence of "easy intubation"

To compare the difference in the incidence of "easy intubation" defined as a patient with Cormack-Lehane I-II glottic view and intubation on the first attempt.

Time frame: During intubation (minutes)

Duration of tracheal intubation

To compare the interval (in seconds) between the first insertion of a videolaryngoscope blade into the mouth and the final placement of an endotracheal tube in the trachea.