Adnexal torsion is the fifth most common gynecologic emergency. Thirty percent of all cases of adnexal torsion occur in females younger than 20 years. Approximately 5 of 100,000 females aged 1-20 years are affected, with girls older than 10 years at increased risk because of hormonal influences and gonadal growth that result in an increased frequency of physiologic and pathologic masses. The most common clinical symptom of torsion is sudden-onset abdominal pain that is intermittent, non-radiating, and associated with nausea and vomiting in 62% and 67% of cases respectively. Moreover, abdominal tenderness is a clinical sign which is reported in up to 88% of patients with adnexal torsion. None of the following tests are useful in the diagnosis of adnexal torsion: leukocytosis, pyuria, C-reactive protein, and erythrocyte sedimentation rate. Actually, transabdominal ultrasonography is the imaging modality of choice with a sensitivity of 92% and specificity of 96% in detecting adnexal torsion. A second-line imaging tool in the diagnosis of adnexal torsion is magnetic resonance, which may require a sedation in selected cases. Consequently, there are no clinical or imaging criteria sufficient to confirm the preoperative diagnosis of adnexal torsion to date. Therefore, patients with a clinical suspicion for adnexal torsion should undergo emergent diagnostic laparoscopy.
Study Type
OBSERVATIONAL
Enrollment
130
All patients in whom preoperative diagnostics have not been able to exclude a surgical pathology and who are candidates for diagnostic-therapeutic surgery will be referred for minimally invasive abdominal exploration in the real suspicion of ovarian torsion. During the pre-operative phase, blood exams will be performed including coagulation which will be integrated with the D-dimer values. In addition, as usual, the clinical examination of the patients will be performed integrated with the various diagnostic image tools generally used in this category of patients (abdomen ultrasound +/- magnetic resonance in urgency).
Medical University of Graz
Graz, Austria
RECRUITINGMedical University of Vienna
Vienna, Austria
RECRUITINGIRCCS Giannina Gaslini
Genova, Italy
RECRUITINGAzienda Ospedale Università Padova
Padua, Italy
RECRUITINGFondazione IRCCS Policlinico San Matteo
Pavia, Italy
RECRUITINGPresidio Ospedaliero Santa Chiara
Trento, Italy
RECRUITINGInstitute for Maternal and Child Health - IRCCS "Burlo Garofolo"
Trieste, Italy
RECRUITINGUniversity of Belgrade
Belgrade, Serbia
RECRUITINGUniversity of Novi Sad
Novi Sad, Serbia
RECRUITINGDiagnostic accuracy of the D-Dimer
Area under the Receiver Operating Characteristic (ROC) curve (AUC) will be assessed to evaluate the diagnostic accuracy of the D-Dimer
Time frame: Through study completion, an average of 18 months
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