Fuzheng Nizeng Formula (FZNZ) is derived from the classic formula Liujunzi Decoction. Former pilot study found that FZNZ promoted the recovery of gastric atrophy and relieve the relative symptoms. This study is to evaluate its efficacy for chronic atrophic gastritis with low-grade intraepithelial neoplasia, compared with positive control Molduodan granule.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
144
Subjects taking prepared Fuzhegn Nizeng granules twice daily for 6 month.
Subjects taking prepared Moluodan granules 9g twice daily for 6 month.
Peking University First Hospital
Beijing, Beijing Municipality, China
RECRUITINGRecovery rate of Low-grade Intraepithelial Neoplasia
Stomach biopsy will be taken after drug administration completion.
Time frame: The 180 days after drug administration.
7-point Global Overall Symptom Scale
Dyspepsia symptoms will be recorded and evaluated by 7-point Global Overall Symptom Scale
Time frame: 1st, 2nd, 3rd, 4th, 5th, 6th month
Adverse event rate
Any adverse event will be recorded.
Time frame: The 6 months during the drug administration
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