This is the first and only study conducted on the use of capnography in children diagnosed with DKA to evaluate the initial clinical grading of DKA, monitor clinical improvement, and predict complications such as brain edema.
Purpose: In this study, the contribution of this non-invasive follow-up method to the management of DKA and the reduction of the frequency of invasive procedures was investigated in patients diagnosed with diabetic ketoacidosis (DKA) in the pediatric emergency department and followed up with capnography Method: This study is a prospective clinical study. Between October 2020- November 2022, EtCO2 and IPI follow-up of 0-18 year-old pediatric patients diagnosed with DKA in the Pediatric Emergency Service of Akdeniz University Medical Faculty Hospital was performed by capnography. DKA diagnosis, grading, clinical follow-up and treatment termination criteria of the patients were determined according to the ISPAD 2018 Diagnosis and Treatment Guidelines. In the study; During the clinical follow-up, changes in GCS, blood glucose, vital, blood gas and capnograph parameters were examined. Demographic data were analyzed in all patients and in groups of patients who underwent DKA grading. GCS, blood gas and capnograph parameters were compared in the patient groups with DKA grading. Diagnostic test performances of blood gas and capnograph parameters were compared to detect low GCS
Study Type
OBSERVATIONAL
Enrollment
55
This is non-invasive follow-up method to the management of DKA and the reduction of the frequency of invasive procedures was investigated in patients diagnosed with diabetic ketoacidosis (DKA) in the pediatric emergency department and followed up with capnography.
Akdeniz University
Antalya, Turkey (Türkiye)
Correlation between PCO2 and EtCO2
The positive linear correlation between PCO2 and EtCO2 indicates that acidosis can be monitored with EtCO2.
Time frame: 2 days
Correlation between Integrated Pulmonary Index and degree of acidosis
Detection of a positive linear correlation between those with Integrated Pulmonary Index \<8 and the degree of acidosis
Time frame: 2 days
Prediction of cerebral edema with Integrated Pulmonary Index
Detection of significant decrease in Glasgow Coma Scale (GCS\<13) in patients with Integrated Pulmonary Index \<4
Time frame: 2 days
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