The aim of this study is to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and bone healing in tooth extraction sockets.
After sample size calculation, healthy volunteers were included in the study. Both teeth of these individuals with bilaterally impacted wisdom teeth were extracted simultaneously. Photobiomodulation (PBM) or leukocyte and platelet rich fibrin (L-PRF), an autogenous blood product, was randomly applied to the right or left side extraction sockets. Volunteers were called for repeat sessions (days 2,4,7,7,11,11,14,18 and 21) for the PBM treated side. Follow-ups were performed for pain (days 2,4,7) and soft and bone tissue healing.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
34
Photobiomodulation application at different extraoral and intraoral points for 60 seconds with a wavelength of 940 nm in repeated sessions after the extraction of third molar
Leukocyte and platelet rich fibrin ( blood product centrifuged for 12 minutes at 2700rpm) application after third molar extraction, single session.
Akdeniz University
Antalya, Merkez, Turkey (Türkiye)
Newly formed bone (Healing at extraction sockets)
Newly formed bone assessed on Panoramic x-ray with Image J programme
Time frame: Bone healing at the end of 1st and 3rd months after third molar extractions
Soft tissue healing
Landry Index scores (1: Very poor, 2: Poor, 3: Good, 4. Very Good, 5. Excellent healing)
Time frame: End of 1st, 2nd week and 1st month after tooth extraction
Probing depth
Probing depth of second mandibular molar distal pocket (millimeters)
Time frame: End of 1st, 2nd week and 1st month after tooth extraction
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.