In Odense University Hospital preoperative dental screening (PDS) protocol for patients treated with Transcatheter Aortic Valve Implantation (TAVI) was changed from mandatory to targeted PDS to between June 2023 to october 2023. The investigators will therefore compare the risk of IE before june 2023 and after october 2023.
Infective endocarditis (IE), a condition linked with significant mortality and morbidity rates, is particularly concerning for patients with prosthetic left-sided valves. These patients face an elevated IE risk, estimated at about 1% annually in tertiary care settings, cumulatively impacting around one in every 20 patients over a decade. In line with this, both the American Heart Association (AHA) and the European Society of Cardiology (ESC) strongly advocate for the elimination of potential dental sepsis sources at least two weeks before prosthetic valve implantation, except in urgent cases. These guidelines, while not grounded in randomized trials, largely draw upon registry data detailing IE incidence among surgical aortic valve replacement (SAVR) patients. In a recent study the investigators found no difference in risk of IE when comparing mandatory preoperative dental screening (MPDS) with no preoperative dental screening (NPDS). Thus, this prospective registry-based observational before-and-after study aims to investigate the impact of different preoperative dental screening practices on the risk of IE in patients undergoing.
Study Type
OBSERVATIONAL
Enrollment
1,000
Discontinuance of mandatory preoperative dental screening prior TAVI which also can include oral surgery.
Odense University Hospital, Cardiology Department
Odense, Denmark
RECRUITINGNumber of Participants with Infectious Endocarditis
Infectious endocarditis diagnosed by healthcare professionals
Time frame: Through study completion, an average of 1 year
Number of Participants undergoing Oral surgical procedure at dental screening
Number of oral surgical procedure performed in patients as part of the dental screening
Time frame: Through study completion, an average of 1 year
Number of Participants undergoing Tooth extraction at dental screening
Number of Tooth extraction procedure performed in patients as part of the dental screening
Time frame: Through study completion, an average of 1 year
The different Bacteria types causing the infectious endocarditis assessed by blood culture
Reporting all the different bacteria type causing infectious endocarditis, including the rate of each bacteria.
Time frame: Through study completion, an average of 1 year
Number patients with Bacteremia assessed by positive blood culture
Cases of bacteremia in the population.
Time frame: Through study completion, an average of 1 year
Number of Participants with IE caused by bacteria from oral foci
Infectious Endocarditis caused by bacteria from oral foci
Time frame: Through study completion, an average of 1 year
Number of Participants with Cardiac implantable electronic device risk of IE
Cardiac implantable electronic device risk of IE
Time frame: Through study completion, an average of 1 year
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