Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis

University of Split, School of Medicine25 enrolled

Overview

Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM. Healthy volunteers will be included (at least 25) and test sites are forearms. Sodium lauryl sulphate will be used to induce contact dermatitis and participants will be measured for 7 days

The efficacy of niacinamide cosmetic product on contact dermatitis will be evaluated using Courage Khazaka device and probes for hydration, redness and transepidermal water loss

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Contact Dermatitis

Interventions

niacinamide cosmetic productOTHER

immortella skincare product

placeboOTHER

nothing

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * young, healthy volunteers who gave written informed consent Exclusion Criteria: * skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation

Locations (1)

University of Split School of Medicine

Split, Croatia

RECRUITING

Outcomes

Primary Outcomes

tewameter

measurement of transepidermal water loss on skin, objective and non invasive

Time frame: day 1- day 7

Central Contacts

JOSIPA BUKIĆ

CONTACT

00385917933752 jbukic@mefst.hr

Data from ClinicalTrials.gov

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