Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness

Istituto Auxologico Italiano66 enrolled

Overview

In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Obstructive Sleep Apnea

Interventions

Tests of upper airway collapsibility and muscle responsiveness.DIAGNOSTIC_TEST

Upper airway collapsibility, upper airway muscle responsiveness and loop gain will be assessed during single study visit. Polysomnography

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Obstructive Sleep Apnea (OSA) * At home-polygraphy with at least one EEG channel (PSG) reporting moderate-to severe obstructive sleep apnea (apnea-hypopnea index \>14). Exclusion Criteria: * OSA treatment ongoing during two weeks before PSG * Unstable cardio-respiratory disease in the 3 months before enrollment * Subjects in O2 treatment

Locations (1)

IRCCS Istituto Auxologico Italiano,Ospedale San Luca

Milan, Italy

RECRUITING

Outcomes

Primary Outcomes

Upper airway collapsibility

Evaluation during wakefulness

Time frame: During the diagnostic test

Upper airway muscle responsiveness

Evaluation during wakefulness

Time frame: During the diagnostic test

Central Contacts

Elisa Perger, MD

CONTACT

+390261911 e.perger@auxologico.it

Data from ClinicalTrials.gov

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