* Comprehensive Investigation of the Impact of Side-Alternating Whole-Body Vibration Training on Muscle Mass and Muscle Strength in Patients with Liver Cirrhosis and Sarcopenia * Simultaneous Characterization and Evaluation of Dynamic Changes in Health-Related Quality of Life in our Patient Cohort with Liver Cirrhosis and Sarcopenia through Side-Alternating Whole-Body Vibration Training.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
15
Side-Alternating Whole-Body Vibration Training
Evaluation of the Effectiveness on muscle strength
Evaluation of the effectiveness of the intervention in terms of muscle strength using the hand-grip-strength
Time frame: 6 months
Evaluation of the Effectiveness on muscle strength
Evaluation of the effectiveness of the intervention in terms of muscle strength using the leg press
Time frame: 6 months
Evaluation of the Effectiveness on muscle strength
Evaluation of the effectiveness of the intervention in terms of muscle strength measuring the gait speed
Time frame: 6 months
Evaluation of the Effectiveness on muscle strength
Evaluation of the effectiveness of the intervention in terms of muscle strength measuring the Timed-Up-And-Go-Test
Time frame: 6 months
Evaluation of the Effectiveness on muscle mass
Evaluation of the Effectiveness on muscle mass through quantification of muscle mass by the skeletal muscle index (SMI) at the level of lumbar vertebral body 3 measured in MRI or CT.
Time frame: 6 months
Evaluation of the Effectiveness on muscle thickness
Evaluation of the Effectiveness on muscle mass through quantification of muscle mass by the transverse psoas muscle thickness (TPMT) at the level of lumbar vertebral body 3 measured in MRI or CT.
Time frame: 6 months
Evaluation of the Effectiveness on mobility, in particular the risk of falling
Evaluation of the Effectiveness on mobility, in particular the risk of falling by using the Tinetti test
Time frame: 6 months
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Evaluation of the Effectiveness on physical function
Evaluation of the Effectiveness on physical function by using the Liver-Frailty-Index
Time frame: 6 months
Evaluation of Safety of the Training Method
Evaluation of the safety of the training method by recording adverse events
Time frame: 12 weeks
Health-Related Quality of Life
Determination of Health-Related Quality of Life by using the Sarcopenia and Quality of Life (SarQoL®) questionnaire. The Sarcopenia and Quality of Life Questionnaire (SarQoL®), a specific questionnaire for assessing quality of life in sarcopenia, consists of 55 items, grouped into 22 questions rated on a 4-point Likert scale. The questionnaire can be scored up to 100 points, with a higher score reflecting a higher quality of life.
Time frame: 6 months
Health-Related Quality of Life
Determination of Health-Related Quality of Life by using the Short Form 36 (SF 36) questionnaire. The possible score ranges from 0 to 100 points, where 0 points represent the greatest possible health impairment, while 100 points indicate no health impairment.
Time frame: 6 months