Despite the increasing popularity of electronic cigarettes (E-cigarettes), the prognostic impact of switching to E-cigarettes in smokers with coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI) remains uncertain.
Recently, several studies have reported that, although lower than combustible cigarette users, E-cigarette users had a significantly higher risk of future myocardial infarction (MI) or cardiovascular disease compared with non-smokers or quitters. However, because all previous studies has focused on the general healthy population, these results cannot be extrapolated for patients who already proven atherosclerotic cardiovascular disease (ASCVD), such as undergoing percutaneous coronary intervention (PCI) for coronary artery disease (CAD). Although Busch et al. previously reported that a significant minority of patients are using E-cigarettes post-acute coronary syndrome smokers, a paucity of data exists regarding the impact of such transitions on clinical outcomes in current smoker patients with CAD who have undergone PCI. In light of these considerations, the current study sought to address this gap in knowledge by evaluating the prognostic implications of smoking habit changes, including E-cigarette use, among CAD patients with current smoking status following PCI.
Study Type
OBSERVATIONAL
Enrollment
17,973
Stop smoking
Switching to E-cigarette
Samsung Medical Center
Seoul, South Korea
MACE
Major adverse cardiac event
Time frame: 5 years after PCI
Cardiovascular death
death from cardiovascular cause
Time frame: 5 years after PCI
All-cause death
death from any cause
Time frame: 5 years after PCI
Spontaneous myocardial infarction
MI with hospitalization
Time frame: 5 years after PCI
Repeat revascularization
additional PCI or CABG
Time frame: 5 years after PCI
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