NCT06340061 - The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters. | Crick | Crick

The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.

N/AUnknownNCT06340061

Henan Provincial People's Hospital80 enrolled

Overview

The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Study Type

OBSERVATIONAL

Enrollment

80

Conditions

Interventions

Observational studyOTHER

The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Eligibility

Sex: ALLMin age: 22 YearsMax age: 79 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of primary glaucoma. * Must be able to cooperate to complete the inspection. Exclusion Criteria: * Secondary glaucoma. * Corneal disease (E. g., keratitis, corneal scarring) that the investigator believes may affect the examination. * trauma * congenital eye malformations

Locations (1)

Henan Provincial People's Hospital

Zhengzhou, Henan, China

Outcomes

Primary Outcomes

IOP

Intraocular pressure

Time frame: through study completion, an average of 2 years.

bIOP

Biomechanical intraocular pressure. Corneal Biomechanics Parameters.

Time frame: through study completion, an average of 2 years.

ACD

Anterior chamber depth. Anterior Chamber Parameters.

Time frame: through study completion, an average of 2 years.

ACW

Anterior chamber width. Anterior Chamber Parameters.

Time frame: through study completion, an average of 2 years.

SSI

Stress-strain index. Corneal Biomechanics Parameters.

Time frame: through study completion, an average of 2 years.

VF

visual field. The severity of glaucoma is mainly based on the damage of the visual field

Time frame: through study completion, an average of 2 years.

Data from ClinicalTrials.gov

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