1. To evaluate the clinical outcomes of ultrasound-guided thermal ablationfor the treatment of benign thyroid nodules; 2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of benign thyroid nodules
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
1,500
microwave ablation, radio frequency ablation, laser ablation
Chinese PLA General Hospital
Beijing, China
RECRUITINGvolume reduction rate
The volume reduction rate (VRR)was calculated by the equations: VRR=(\[initial volume-final volume\] × 100)/initial volume
Time frame: through study completion, an average of 6 months
rate of nodule regrowth
Regrowth was defined as ≥50% volume increase compared to the previously recorded smallest volume during the follow-up
Time frame: through study completion, an average of 1 months
rate of complications
complications after ablation
Time frame: 1 week
cosmetic score
The cosmetic score was assessed by a physician (1, no palpable mass; 2, no cosmetic problem but palpable mass; 3, a cosmetic problem on swallowing only; and 4, a readily detected cosmetic problem)
Time frame: through study completion, an average of 6 months
symptom score
The symptom score was self-measured by patients using a 10-cm visual analogue scale (grade 0-10)
Time frame: through study completion, an average of 6 months
vital volume
vital volume was the incompletely treated vital volume which located peripherally
Time frame: through study completion, an average of 6 months
total volume
the overall volume of the nodules
Time frame: through study completion, an average of 6 months
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