The purpose of this study is to investigate whether bariatric surgery affects Drospirenone only pills absorption
After being informed about the study and potential risks, all participants giving written informed consent who meet the eligibility requirements will take Drospirenone-only pills (4 mg, once daily). Between the 21st and 28th day of Drospirenone taking, pharmacokinetics will be measured. Pre-bariatric surgery pharmacokinetics study will be compared with post-bariatric surgery pharmacokinetics study.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
16
4 mg tablet once daily
Chulalongkorn University
Bangkok, Thailand
RECRUITINGPlasma concentration versus Time of Drospirenone
Plasma concentration of Drospirenone will be measured at 0, 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6, 8 hours post-dose
Time frame: 1 month before and 1 month after bariatric surgery
Number of Participants With Treatment-Related Adverse Events
Time frame: 1 month
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