The purpose of this study is to study the effect of Drospirenone on cervical mucus change by modified Insler score, pre-bariatric surgery and post-bariatric surgery
After being informed about the study and potential risks, all participants giving written informed consent who meet the eligibility requirements will take Drospirenone-only pills (4 mg, once daily). Cervical mucus by modified Insler score will be evaluated on Day 4-7 of Drospirenone taking. Pre-bariatric surgery results will be compared with post-bariatric surgery results.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
16
4 mg tablet once daily
Chulalongkorn University
Bangkok, Thailand
RECRUITINGCervical mucus by modified Insler score
Modified Insler score (ferning, spinnbarkeit, viscosity, cellularity) according to the World Health Organization (WHO) guidelines 2010 used for prediction and detection of ovulation. Score ≥9 favoring fertility, 5-8 intermediate, and ≤4 unfavorable to fertility Comparing pre-bariatric surgery with post-bariatric surgery
Time frame: 1 month before and 1 month after bariatric surgery
Estrogen and progesterone levels versus time
Serum estrogen and progesterone levels will be measured to evaluate change over time (pattern and value) and assess ovulation
Time frame: 1 month before and 1 month after bariatric surgery
Number of Participants With Treatment-Related Adverse Events
Time frame: 1 month
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