Abdominal surgery causes severe postoperative pain due to retraction of the abdominal wall and direct manipulation of visceral organs. It leads to delayed postoperative recovery, increased postoperative morbidity and mortality. Intrathecal morphine, epidural analgesia and patient-controlled intravenous analgesia are used in postoperative pain management of abdominal surgeries. Intrathecal morphine is frequently used in many centers because it provides effective pain control. However; morphine has undesirable effects such as urinary retention, postoperative nausea and vomiting, and respiratory depression. Modified thoracoabdominal nerves block through perichondrial approach is a technique defined by the modification of the thoracoabdominal nerves block through perichondrial approach, in which local anesthetics are delivered only to the underside of the perichondral surface. The primary implication of this study is to compare postoperative pain scores and opioid consumption in patients undergoing major abdominal surgery with intrathecal morphine or modified thoracoabdominal nerves block through perichondrial approach.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SCREENING
Masking
SINGLE
Enrollment
56
Comparing postoperative pain and opioid consumption in groups
Marmara University School of Medicine
Istanbul, Turkey (Türkiye)
Comparison of postoperative opioid consumption between two groups via Patient Controlled Analgesia (PCA) device
Intravenous patient-controlled analgesia (PCA) is a system of opioid delivery that consists of an infusion pump interfaced with a timing device. Intravenous morphine consumption will be recorded via PCA device, then it will be documented in mg/kg units.
Time frame: 48 hours
Postoperative pain assessment with Numeric Rating Scale (NRS)
In a Numerical Rating Scale (NRS), patients are asked to choose the number
Time frame: 48 hours
Comparison of the frequency of treatment related complications
Bradycardia, hypotension, sedation, respiratory depression, urinary retention, itching, need for rescue analgesics.
Time frame: 48 hours
Participant satisfaction
Whether the patient is very pleased/ satisfied/ unsatisfied/ complainant with the pain treatment will be recorded.
Time frame: 48 hours
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