The purpose of the study is to examine the effects of continuous theta burst stimulation (cTBS) on different forms of cognitive control in adults who smoke cigarettes, and to determine if the location where cTBS is delivered may help smokers reduce or quit smoking. Participation in the study will take 3-weeks over 4 visits, with a total time commitment of approximately 12 hours.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
30
Continuous theta burst rTMS
Health Neuroscience Center
Columbia, Missouri, United States
RECRUITINGAcute effects of cTBS on cognitive control
between-arm differences in neurocognitive task performance as measured by percent correct on an inhibitory control task and self reported craving on a regulation of craving task.
Time frame: 1 hour after receiving cTBS
Exploratory: Acute effects of cTBS on fMRI brain response
between-arm differences in whole brain fMRI BOLD functional connectivity. Neural network connectivity will be characterized using rZ values.
Time frame: 1 hour after receiving cTBS
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