A 3-Arm Study Comparing the Efficacy of Anti-Reflux Reconstruction Protocols After Laparoscopic Proximal Gastrectomy

Inclusion Criteria: 1. Age between 18-75 years old, male or female; 2. Eastern Cooperative Oncology Group (ECOG) performance status of 0 (indicating fully active and able to continue all predisease activities without restriction) or 1 (indicating restricted in physically strenuous activities but ambulatory and able to perform work of a light or sedentary nature); 3. American Society of Anesthesiology physical status classification of I (indicating normal and healthy), II (indicating mild systemic disease), or III (indicating severe systemic disease); 4. Pathological diagnosis of preoperative endoscopic biopsy: the tumor is located in the upper 1/3 of the stomach (including the esophagogastric junction), and the clinical staging of gastric cancer Ia and Ib (T1N0M0, T1N1M0, and T2N0M0) (14) according to the eighth edition of the AJCC; 5. Patients without contraindications to surgery; 6. Voluntary participation by signing the written informed consent form approved by the institutional review board before study participation; Exclusion Criteria: 1. Receipt of chemotherapy or radiotherapy for the treatment of GC before either surgical procedure 2. Combined resection required due to other diseases (except cholecystectomy). 3. History of cancer or concurrent cancer in other organs. 4. Previous or current receipt of treatment for systemic inflammatory disease or history of gastrectomy. 5. Patients with coagulation dysfunction which could not be corrected; 6. Vulnerable status (eg, lacking decision-making capacity, pregnant, or planning to become pregnant). 7. Receipt of chemotherapy or radiotherapy before either surgical procedure.