To investigate the incidence, predictive markers, and survival impact of massive nasal bleeding in nasopharyngeal carcinoma (NPC) patients who received curative radiotherapy (RT) with/without chemotherapy. A total of 1327 patients with previously untreated, biopsy-proven NPC, and no distant metastasis were retrospective reviewed. Investigators analyzed the occurrence rates of massive nasal bleeding between different characteristics and tried to identify important predictive factors. Investigators compared overall survival between patients with and without massive nasal bleeding by Kaplan-Meier method.
Study Type
OBSERVATIONAL
Enrollment
1,327
No event of massive nasal bleeding after curative radiotherapy
Any event of massive nasal bleeding after curative radiotherapy
Taichung Veterans General Hospital
Taichung, Taiwan
Massive Nasal Bleeding Rate
Massive Nasal Bleeding Rate among different characteristics. Massive Nasal Bleeding was defined as unique blood loss \> 300 ml or recurrent blood losses \> 100 ml.
Time frame: From date of radiotherapy until the date of first documented massive bleeding, assessed up to 360 months
Overall Survival
Overall Survival
Time frame: From date of radiotherapy until the date of last clinic visit or date of death from any cause, whichever came first, assessed up to 360 months
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