The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation

Alexandria University120 enrolled

Overview

The aim of the current study is to assess the desensitising effect of nanosilver fluoride on first permanent molars (FPMs) in patients with MIH in comparison to low-level laser therapy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

120

Conditions

Molar Incisor Hypomineralization Hypersensitivity

Interventions

Low-level laser therapyDEVICE

Wavelength 980nm (SmartM, Lasotronix, Poland)

Nanosilver fluorideDRUG

Optimized synthesis of Nanosilver Fluoride

Eligibility

Sex: ALLMin age: 7 YearsMax age: 10 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The presence of at least one hypersensitive first permanent molar in MIH patient (using the Schiff Cold Air Sensitivity Scale (SCASS)). * Completion of an informed consent to participate in the study. Exclusion Criteria: * Hypomineralised molars resulting from other medical conditions, such as enamel malformations associated with syndromes, dental fluorosis, enamel hypoplasia, amelogenesis imperfecta, and dental caries. * The presence of active tooth decay or defective restorations in the tooth under examination which can confound the aetiology of hypersensitivity with pulpitis. * The presence of pulpal symptoms. * Having undergone any professional desensitising treatment in the previous 6 months. * Having used a desensitising paste other than habitual toothpaste in the previous 3 months. * Use of anti-inflammatory drugs or analgesics at the time of recruitment. * Allergy or sensitivity to silver or any of the materials included in the study.

Locations (1)

Faculty of Dentistry, Alexandria University

Alexandria, Egypt

Outcomes

Primary Outcomes

Desensitising effect in hypersensitive MIH molars

This will be performed using Schiff Cold Air Sensitivity Scale (SCASS). The SCASS will be used to assess subject response to this stimulus (0=no response to the stimulus; 1=no response to the stimulus, patient considers stimulus to be painful; 2= response to stimulus, patient moves from the stimulus; 3= response to the stimulus, patient moves from the stimulus and requests immediate discontinuation of the stimulus)

Time frame: 1 month

Secondary Outcomes

Change in the plaque index scores

This will be assessed using the modified plaque index (PlI) of Silness and Löe. Each tooth will be scored from 0 (lowest) to 3 (highest) according to the amount of plaque accumulation. The total score will be determined by calculating the average score of the examined teeth.

Time frame: 1 month

Change in children's frequency of toothbrushing

The frequency of toothbrushing will be assessed using a question adapted from the World Health Organization (WHO) questionnaire- child version. The parent will be asked about the number of times his/her child brushes their teeth (never - several times a month - once a week - several times a week - once daily - twice or more daily)

Time frame: 1 month

Data from ClinicalTrials.gov

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