Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study

Aya Ayman Ahmed2 enrolled

Overview

Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures via Intraoral Versus Extraoral Approaches: Prospective Cohort Study

Study Type

OBSERVATIONAL

Enrollment

Conditions

Mandibular Fractures

Interventions

Open Reduction & Internal FixationPROCEDURE

Open Reduction \& Internal Fixation of Mandibular fracture either through intraoral or extraoral approaches.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Single mandibular fracture. * ORIF is done by two plates fixation with titanium plates and screws. * Age (18-50 years). * Recent fracture (less than 2 weeks). Exclusion Criteria: * Pathological fractures. * Medical compromised patient. * Presence of concomitant injuries. * Patients receive radiotherapy. * Patients receive blood transfusion.

Outcomes

Primary Outcomes

IL-17

Interleukin-17

Time frame: 6- weeks

OPG

Osteoprotegerin

Time frame: 6- weeks

Secondary Outcomes

Blood Loss

Time frame: in operation room

Operative time

Time frame: Operative time in minutes

Data from ClinicalTrials.gov

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