Natural orifice specimen extraction surgery (NOSES) has gained widespread recognition among scholars and has gradually been promoted and popularized around the world. However, the development of NOSES is still in the exploratory stage and there is a lack of strong evidence from evidence-based medicine to support its feasibility and safety, which has greatly affected its clinical application and development. Based on this, at the call of Professor Xishan Wang, the Chinese NOSES Alliance conducted a large retrospective clinical study involving multiple centers. By summarizing the NOSES cases of nearly 100 centers in China, the study aims to clarify the current status of NOSES surgery in China. Additionally, a comprehensive analysis and summary was conducted by combining the basic information of NOSES patients, perioperative data, postoperative pathological data, and follow-up information to further demonstrate the safety and feasibility of NOSES in the treatment of colorectal cancer. This study also provides more real and objective evidence-based medicine support for the promotion and development of NOSES surgery.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
8,000
We perform laparoscopic colorectal cancer resection, intracorporeal anastomosis and transanal or transvaginal specimen extraction
Cancer Hospital Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China
RECRUITINGRate of short-term complication
Rate of complications occurred within 30 days after surgery
Time frame: 30 days after surgery
Operative duration
Total time of the operation
Time frame: 7 days
Intraoperative blood loss
Estimated blood loss during the surgery
Time frame: 7 days
Time to first flatus after surgery
Time to first flatus after surgery
Time frame: 7 days
Time to first stool after surgery
Time to first stool after surgery
Time frame: 7 days
Length of stay after surgery
Length of stay after surgery
Time frame: 7 days
3-year disease free survival
3-year disease free survival
Time frame: 3 year
3-year overall survival
3-year overall survival
Time frame: 3 year
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