This standardized prospective long-term outcome analysis will help reaffirm these findings via a multicenter patient cohort and describe the best practices/techniques for stabilization of the autograft and right ventricular outflow tract reconstruction.
The optimal approach for aortic valve replacement in adults with an anticipated life expectancy greater than fifteen years remains unclear. Mechanical and bioprosthetic valves, while often used, have specific downfalls. Mechanical valves require lifelong anticoagulation usage and bioprosthetic tissue valves have a limited lifespan. The Ross procedure (pulmonary autograft replacement) is the only operation which replaces the diseased aortic valve with a living substitute. Concerns over increased surgical risk and potential long-term failure have shown decreased use of this procedure. However, recent publications from expert centers have shown, in the current era the Ross procedure can be reliably performed safely and reproducibly in selected patients. This standardized prospective long-term outcome analysis will help reaffirm these findings via a multicenter patient cohort and describe the best practices/techniques for stabilization of the autograft and right ventricular outflow tract reconstruction.
Study Type
OBSERVATIONAL
Enrollment
225
Baylor Scott and White Heart Hospital
Plano, Texas, United States
RECRUITINGSurvival of the patient
The primary endpoint of this study will be survival at 1-, 5-, and 10-year intervals.
Time frame: 1 year, 5 year and 10 year
Rate of re-hospitalization
To identify the safety of the Ross procedure measured in percentage
Time frame: 1 year after the procedure
Rate of peri operative morbidity
Will be measured in percentage
Time frame: 1 year after the procedure
Rate of re-operation
Will be measured in percentage
Time frame: 1 year after the procedure
Rate of re-intervention
will be measured in percentage
Time frame: 1 year after the procedure
NYHA status
Will be measured as NYHA class I, II,III, IV
Time frame: 1 year after the procedure
Rate of Patients with Anticoagulant Usage
Rate of Patients with Anticoagulant Usage 1 year after procedure.
Time frame: 1 year after the procedure
Rate of Bleeding Events
Rate of Bleeding Events
Time frame: 1 year after the procedure
Rate of Post Operative Infection
Rate of Post Operative Infection
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: 1 year after the procedure