The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with ST-segment myocardial infarction (STEMI). Randomization will be performed after successful culprit-lesion guidewire crossing and flow restoration. Random allocation in a 1:1 fashion to one of the following strategies: * Study group: reduced stent PCI strategy (DCB-based) * Control group: conventional PCI strategy (DES-based).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
1,272
Coronary percutaneous revascularization
Hospital Universitario Juan Ramón Jiménez
Huelva, Huelva, Spain
RECRUITINGHospital Universitario Y Politecnico La Fe
Valencia, Valencia, Spain
RECRUITINGComplejo Hospitalario Universitario de A Coruña
A Coruña, Spain
RECRUITINGHospital Universitario de Burgos
Burgos, Spain
RECRUITINGConsorcio Hospitalario Provincial de Castellon
Castelló, Spain
RECRUITINGHospital Universitario Reina Sofía de Córdoba
Córdoba, Spain
RECRUITINGHospital General Universitario de Elche
Elche, Spain
RECRUITINGHospital Universitario Clínico San Cecilio
Granada, Spain
RECRUITINGHospital Universitari de Bellvitge
L'Hospitalet de Llobregat, Spain
RECRUITINGHospital Universitario de La Princesa
Madrid, Spain
RECRUITING...and 13 more locations
Target lesion failure (TLF)
Target-vessel myocardial infarction or ischemia-driven target-lesion revascularization
Time frame: 12 months
Incidence of all-cause death
Physicians Assessment
Time frame: 10 years
Incidence of myocardial infarction
Physicians Assessment
Time frame: 10 years
Incidence of cardiovascular death
Physicians Assessment
Time frame: 10 years
Incidence of target lesion revascularization
Physicians Assessment
Time frame: 10 years
Incidence of stent thrombosis
Physicians Assessment
Time frame: 10 years
Incidence of acute vessel closure
Physicians Assessment
Time frame: 10 years
Incidence of stroke
Physicians Assessment
Time frame: 10 years
Incidence of acute kidney injury
Physicians Assessment
Time frame: 10 years
Incidence of bleeding
Physicians Assessment
Time frame: 10 years
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