Differential Expression and Potential Value of c-MYC in Non-Invasive and Invasive Mammary Carcinoma

Marwa Mahmoud Hassan70 enrolled

Overview

Retrospective observational study to evaluate c-MYC expression in non invasive and invasive mammry carcinoma

To correlate different levels of c-MYC expressions with variable clinical and pathological parameters of mammary carcinoma (such as patients' ages, tumor grading, staging, laterality, focality and nodal metastasis, co-existing in-situ components). This study will be carried out on archived formalin-fixed and paraffin embedded tissue blocks that were belonged to 70 women with breast lumps.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Invasive Breast Cancer

Interventions

no interventionOTHER

No intervention

Eligibility

Sex: FEMALEMin age: 15 Years

Medical Language ↔ Plain English

Inclusion Criteria: Specimens of Modified Radical Mastectomies from breast carcinoma patients Exclusion Criteria: * Cases with insufficient clinical data. * Tissue blocks of destroyed or insufficient material, unfit for diagnosis. * Cases who received pre-operative chemotherapy.

Locations (1)

Sohag university

Sohag, Egypt

Outcomes

Primary Outcomes

role of c-MYC in breast cancer

difference between expression of c-MYC in non invasive and invasive mammary carcinoma

Time frame: 1 year

Data from ClinicalTrials.gov

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